Thursday, 13 September 2012

Chantix



Generic Name: varenicline (ver EN e kleen)

Brand Names: Chantix


What is varenicline?

Varenicline is a smoking cessation medicine. It is used together with behavior modification and counseling support to help you stop smoking.


Varenicline may also be used for purposes not listed in this medication guide.


What is the most important information I should know about varenicline?


Before using varenicline, tell your doctor if you have heart disease, circulation problems, kidney disease, or a history of depression or mental illness. You may choose from 2 ways to use varenicline. Ask your doctor which of the following methods is best for you: To improve your chances for successful smoking cessation, be sure to quit smoking on your planned quit date.

After you stop smoking, the doses of any medications you are using may need to be adjusted. Tell your doctor about all other medicines you use, especially insulin, blood thinners, or asthma medication.


Stop using this medication and call your doctor at once if you have: any mood or behavior changes, confusion, anxiety, panic attacks, hallucinations, extreme fear, or if you feel impulsive, agitated, aggressive, restless, hostile, depressed, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself. Varenicline may impair your thinking or reactions. You may also have mood or behavior changes when you quit smoking. Until you know how varenicline and the smoking cessation process is going to affect you, be careful if you drive or do anything that requires you to be cautious and alert.

What should I discuss with my health care provider before taking varenicline?


To make sure you can safely take varenicline, tell your doctor if you have any of these other conditions:

  • heart disease, circulation problems;




  • kidney disease (or if you are on dialysis); or




  • a history of depression or mental illness.




FDA pregnancy category C. It is not known whether varenicline will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether varenicline passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to anyone under 18 years old

How should I take varenicline?


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.


You may choose from 2 ways to use varenicline. Ask your doctor which of the following methods is best for you:

  • Set a date to quit smoking and start taking varenicline one week before that date. This will allow the drug to build up in your body.




  • You may also start taking varenicline before you set a planned quit date. Once you start taking the medicine, choose a quit date that is between 8 and 35 days after you start treatment.




To improve your chances for successful smoking cessation, be sure to quit smoking on your planned quit date. Take varenicline after eating. Take the medicine with a full glass of water.

When you first start taking varenicline, you will take a low dose and then gradually increase your dose over the first several days of treatment. Follow your doctor's dosing instructions very carefully.


In most cases, varenicline treatment lasts for 12 weeks. Your doctor may recommend a second 12-week course of varenicline to improve the chance that you will quit smoking long-term.


Use varenicline regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely. You should remain under the care of a doctor while taking varenicline.


Store at room temperature away from moisture and heat.

What happens if I miss a dose?


Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking varenicline?


This medication may impair your thinking or reactions. You may also have mood or behavior changes when you quit smoking. Until you know how varenicline and the smoking cessation process are going to affect you, be careful if you drive or do anything that requires you to be cautious and alert.

Do not use other medications to quit smoking while you are taking varenicline, unless your doctor tells you to.


Varenicline side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any mood or behavior changes, confusion, anxiety, panic attacks, hallucinations, extreme fear, or if you feel impulsive, agitated, aggressive, restless, hostile, depressed, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Your family or other caregivers should also be alert to changes in your mood or behavior.


Call your doctor at once if you have any of these other serious side effects:

  • chest pain or pressure, tight feeling in your neck or jaw, pain spreading to your arm or shoulder, vomiting, sweating, general ill feeling;




  • feeling light-headed or short of breath;




  • sudden numbness or weakness, especially on one side of the body;




  • sudden severe headache, confusion, problems with vision, speech, or balance;




  • easy bruising, unusual bleeding, blood in your urine or stools, coughing up blood or vomit that looks like coffee grounds;




  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or




  • the first sign of any blistering type of skin rash, no matter how mild.



Less serious side effects may include:



  • nausea (may persist for several months);




  • stomach pain, indigestion, constipation, gas;




  • weakness, tired feeling;




  • dry mouth, unpleasant taste in your mouth;




  • headache; or




  • sleep problems (insomnia) or unusual dreams.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect varenicline?


After you stop smoking, the doses of any medications you are using may need to be adjusted. Tell your doctor about all other medicines you use, especially:



  • insulin;




  • a blood thinner such as warfarin (Coumadin, Jantoven); or




  • asthma medication such as theophylline (Respbid, Theobid, Theoclear, Theo-Dur, Uniphyl).



This list is not complete and other drugs may interact with varenicline. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Chantix resources


  • Chantix Side Effects (in more detail)
  • Chantix Use in Pregnancy & Breastfeeding
  • Drug Images
  • Chantix Drug Interactions
  • Chantix Support Group
  • 369 Reviews for Chantix - Add your own review/rating


  • Chantix Prescribing Information (FDA)

  • Chantix Monograph (AHFS DI)

  • Chantix Advanced Consumer (Micromedex) - Includes Dosage Information

  • Chantix Consumer Overview

  • Chantix MedFacts Consumer Leaflet (Wolters Kluwer)

  • Varenicline Professional Patient Advice (Wolters Kluwer)



Compare Chantix with other medications


  • Smoking Cessation


Where can I get more information?


  • Your pharmacist can provide more information about varenicline.

See also: Chantix side effects (in more detail)


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